Estudo da Colonização por Streptococcus Agalactiae em Gestantes atendidas na Maternidade Escola da Universidade Federal do Rio de Janeiro

Abstract

This study evaluated the vaginal/anal colonization by Streptococcus agalactiae among 167 pregnant women between 32nd and 41st weeks of gestation, attended in the prenatal ambulatory of the School Maternity of Rio de Janeiro University (UFRJ), during the period from february 2003 to february 2004. The frequency of colonization was of 19,2%, without significant differences when variants like age, number of gestations, premature delivery in previous pregnancies, number of abortions and the presence or absence of diabetes (p>0,05) were compared. All 32 strains isolated were susceptible to penicillin, cefotaxime, ofloxacin, chloramphenicol, vancomycin and meropenem. Resistance to penicillin of two strains, as detected by disk diffusion susceptibility test, was not confirmed by dilution antimicrobial susceptibility tests. The concomitant resistance to clindamycin and erythromycin was verified in 2 strains; these presented the constitutive MLSB phenotype. The isolate resistant only to erythromycin presented the M phenotype. The relatively high incidence (19,2%) of colonization by S. agalactiae among the pregnant women evaluated and the recovery of antimicrobial resistant strains, specialy those recommended in cases of penicillin allergy, emphasize the importance, for a correct prevention of neonatal infections, to detect colonization at the end of pregnancy and to evaluate the antimicrobial susceptibility of S. agalacti